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Qian Wu, Xinrong Zhou, Zizhan Ma, Kai Chen, Zheyao Gao, Xun Lin, Hongqiu Wu, Longfei Gou, Yixiao Liu, Ann Sin Nga Lau, Qi Dou
Large Language Models (LLMs) show promise for medical education, but most existing systems focus on localized interactions such as question answering or single-turn feedback, rather than organizing an entire clinical case into a decision-centered learning trajectory. We introduce \textit{MedGame}, a framework that transforms static clinical cases into structured, executable storytelling games. MedGame uses a dual-engine design: a Medical Narrative Designer synthesizes case-grounded clinical storylines with states and decision nodes, while a Story Director converts them into dependency-aware multimodal orchestration plans rendered by our released interactive platform. We construct MedGame Bench, a 5,000-case benchmark and evaluation protocol for Medical Narrative Generation and Story Direction. Experiments show that task-specific fine-tuning substantially improves open-source LLMs on MedGame Bench and narrows the gap with commercial models. A pilot student study further shows that learners perceive MedGame as more engaging and useful than text-only alternatives.
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@article{wu2026medgame,
title = {MedGame: Storytelling Gamification Empowered by Large Language Models for Medical Education},
author = {Qian Wu and Xinrong Zhou and Zizhan Ma and Kai Chen and Zheyao Gao and Xun Lin and Hongqiu Wu and Longfei Gou and Yixiao Liu and Ann Sin Nga Lau and Qi Dou},
year = {2026},
abstract = {Large Language Models (LLMs) show promise for medical education, but most existing systems focus on localized interactions such as question answering or single-turn feedback, rather than organizing an entire clinical case into a decision-centered learning trajectory. We introduce \textbackslash{}textit\{MedGame\}, a framework that transforms static clinical cases into structured, executable storytelling games. MedGame uses a dual-engine design: a Medical Narrative Designer synthesizes case-grounded clinical stor},
url = {https://arxiv.org/abs/2607.21570},
keywords = {cs.CL, cs.HC},
eprint = {2607.21570},
archiveprefix = {arXiv},
}
{}