Paper Detail
Rafsan Jany, Shadab Tanjeed Ahmad, Ahsan Bulbul, Tahsinul Islam, Md Azam Hossain, Abu Raihan Mostofa Kamal
Multimodal based approaches often outperform single modality approaches in downstream tasks as the different modalities provide complementary information, yet acquiring paired clinical data remains a significant challenge in real world scenarios. While cross-modal knowledge distillation addresses this, existing methods often struggle with large modality gaps and the propagation of noise from uncertain source-domain predictions. To overcome these challenges, we propose UnDA, an anchor-guided framework for unpaired cross-modal distillation. Our approach introduces a backbone-agnostic Alignment Module that extracts semantically structured class tokens via an attention based pooling mechanism. To ensure robust knowledge transfer, we propose Uncertainty-Weighted Optimal Transport (UCT-OT), which dynamically weights feature-level alignment based on prediction confidence, effectively suppressing noisy supervision. Furthermore, a per-class ProtoNCE objective maintains stable prototype memories to enforce global discriminability across unpaired batches. Evaluations on representative segmentation tasks under strictly unpaired settings show consistent improvements in accuracy and boundary precision in the target modality, demonstrating that meaningful structural knowledge can be transferred across heterogeneous data sources without paired datasets.
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@article{jany2026unda,
title = {UnDA: Unpaired Domain Alignment for Cross-Modal Knowledge Transfer in Medical Imaging},
author = {Rafsan Jany and Shadab Tanjeed Ahmad and Ahsan Bulbul and Tahsinul Islam and Md Azam Hossain and Abu Raihan Mostofa Kamal},
year = {2026},
abstract = {Multimodal based approaches often outperform single modality approaches in downstream tasks as the different modalities provide complementary information, yet acquiring paired clinical data remains a significant challenge in real world scenarios. While cross-modal knowledge distillation addresses this, existing methods often struggle with large modality gaps and the propagation of noise from uncertain source-domain predictions. To overcome these challenges, we propose UnDA, an anchor-guided fram},
url = {https://arxiv.org/abs/2607.21546},
keywords = {cs.CV},
eprint = {2607.21546},
archiveprefix = {arXiv},
}
{}