Paper Detail

Case-Specific Rubrics for Clinical AI Evaluation: Methodology, Validation, and LLM-Clinician Agreement Across 823 Encounters

Aaryan Shah, Andrew Hines, Alexia Downs, Denis Bajet, Paulius Mui, Fabiano Araujo, Laura Offutt, Aida Rutledge, Elizabeth Jimenez

arxiv Score 8.3

Published 2026-04-27 · First seen 2026-04-28

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Abstract

Objective. Clinical AI documentation systems require evaluation methodologies that are clinically valid, economically viable, and sensitive to iterative changes. Methods requiring expert review per scoring instance are too slow and expensive for safe, iterative deployment. We present a case-specific, clinician-authored rubric methodology for clinical AI evaluation and examine whether LLM-generated rubrics can approximate clinician agreement. Materials and Methods. Twenty clinicians authored 1,646 rubrics for 823 clinical cases (736 real-world, 87 synthetic) across primary care, psychiatry, oncology, and behavioral health. Each rubric was validated by confirming that an LLM-based scoring agent consistently scored clinician-preferred outputs higher than rejected ones. Seven versions of an EHR-embedded AI agent for clinicians were evaluated across all cases. Results. Clinician-authored rubrics discriminated effectively between high- and low-quality outputs (median score gap: 82.9%) with high scoring stability (median range: 0.00%). Median scores improved from 84% to 95%. In later experiments, clinician-LLM ranking agreement (tau: 0.42-0.46) matched or exceeded clinician-clinician agreement (tau: 0.38-0.43), attributable to both ceiling compression and LLM rubric improvement. Discussion. This convergence supports incorporating LLM rubrics alongside clinician-authored ones. At roughly 1,000 times lower cost, LLM rubrics enable substantially greater evaluation coverage, while continued clinical authorship grounds evaluation in expert judgment. Ceiling compression poses a methodological challenge for future inter-rater agreement studies. Conclusion. Case-specific rubrics offer a path for clinical AI evaluation that preserves expert judgment while enabling automation at three orders lower cost. Clinician-authored rubrics establish the baseline against which LLM rubrics are validated.

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BibTeX

@article{shah2026case,
  title = {Case-Specific Rubrics for Clinical AI Evaluation: Methodology, Validation, and LLM-Clinician Agreement Across 823 Encounters},
  author = {Aaryan Shah and Andrew Hines and Alexia Downs and Denis Bajet and Paulius Mui and Fabiano Araujo and Laura Offutt and Aida Rutledge and Elizabeth Jimenez},
  year = {2026},
  abstract = {Objective. Clinical AI documentation systems require evaluation methodologies that are clinically valid, economically viable, and sensitive to iterative changes. Methods requiring expert review per scoring instance are too slow and expensive for safe, iterative deployment. We present a case-specific, clinician-authored rubric methodology for clinical AI evaluation and examine whether LLM-generated rubrics can approximate clinician agreement. Materials and Methods. Twenty clinicians authored 1,64},
  url = {https://arxiv.org/abs/2604.24710},
  keywords = {cs.AI, cs.CL},
  eprint = {2604.24710},
  archiveprefix = {arXiv},
}

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